About a year ago I came across a note taking format that I really liked. It was actually the Notebook layout in MS Word. This sort of layout - like an old fashion notebook (with the ability to do oral notes as well) really appealed to me. This led me on a hunt for some sort of mac equivalent.
This was when I came across a free program called "Growly Notes". A free program that does quite a lot. It is generously put out by two people (a couple I think) who have designed and produced a number of mac based "home" programs.
You can add booklets and pages; incorporate video and sound; draw notes on pages etc. Worth checking out.
Have a look at